December 25th, 2025
If you’ve noticed more posts or ads promising calm energy, focus, or pain relief from something called kratom or 7-OH, you’re seeing a digital turf war unfold. Each side, kratom sellers and 7-OH promoters, has built a small industry of influencers and even automated bots to flood social media with glowing reviews.
Both substances come from the same plant, Mitragyna speciosa, but 7-OH (short for 7-hydroxymitragynine) is a much stronger version. What’s being sold as “natural” or “safe” can act on the same brain receptors as opioids. Unfortunately, the loudest voices online often hide the truth about risks of addiction [1] [2].
Kratom is a tropical tree from Southeast Asia whose leaves contain natural chemicals that affect the brain. The main one is mitragynine. When mitragynine is processed in the body, or extracted in a lab, it turns into 7-OH, which is far more powerful. While some researchers think results are inconclusive or that kratom is the “lesser of two evils” as compared to the opiates some people use it to replace, others are confident that kratom can be addictive [2].
Researchers are more conclusive about 7-OH. They have found that 7-OH hits opioid receptors more strongly and can be hundreds of times more potent than the original kratom leaf. That means a “natural” powder or extract can still trigger real dependence and withdrawal, often very quickly. In an ongoing joint research project conducted by Windmill Wellness Ranch and Johns Hopkins University, study participants reported intense withdrawals and tolerance within days of starting 7-OH use.
Online, each side fights for market share. Kratom fans post personal stories about how it helped them quit opioids or manage anxiety. 7-OH sellers call their products “cleaner” or “stronger.” But behind the scenes, researchers have found evidence of coordinated, and often deceptive [3], marketing campaigns. There is strong suspicion that marketing companies are using bots and paid marketers posing as ordinary users to drown out cautionary voices.
One study found that the majority of YouTube videos about kratom focused on positive experiences, with fewer warnings about risks [4]. The result? People scrolling online may believe kratom or 7-OH are harmless herbs when, in reality, they can lead to serious dependence and life problems.
Even “small” amounts can cause nausea, rapid heart rate, sweating, anxiety, insomnia, and agitation. With higher doses or frequent use, people report tremors, constipation, depressed mood, and rebound pain. Stopping suddenly can bring withdrawal—restlessness, sleeplessness, muscle aches, irritability, diarrhea, and strong cravings.
Never mix kratom or 7-OH with alcohol, opioids, benzodiazepines, or sedatives. Combining them raises the risk of breathing problems, loss of consciousness, and overdose-level events—especially with concentrated extracts.
Poison-control centers and hospitals are seeing more kratom-related emergencies every year. Reported effects include rapid heart rate, agitation, seizures, and liver problems [5]. Kratom products are usually openly sold in smoke shops— with some reports showing this happens even in areas where it’s restricted.
Because 7-OH is so strong, even small doses can cause serious problems, especially when combined with alcohol, opioids, or anxiety medications. Larger doses, which many people turn to as tolerance builds quickly, can even become fatal, especially when combined with other substances [6].
If you’re reading about kratom or 7-OH online, keep an eye out for these warning signs of marketing spin:
If it sounds too good to be true, it probably is.
At Windmill Wellness Ranch, we’re seeing more people struggling with kratom and 7-OH dependence—and we’re doing something about it. We’ve been warning about the dangers of kratom and 7-OH, and we’ve been treating the people who have fallen prey to deceptive marketing and the hidden dangers of these drugs.
We’ve partnered with Johns Hopkins University to study how these substances affect the brain and how best to support long-term recovery. Our approach combines:
If home use, withdrawal, or mood swings are taking over your life, residential care can provide the structure and safety needed to reset. At Windmill Wellness Ranch, we specialize in compassionate, evidence-based treatment for both addiction and trauma, helping individuals and families rebuild stability and hope. If you or someone you love needs support, we are here. Call 830-223-2055 or contact us online to take the first step toward healing.
1. Reif, B., Adkins, A., Boyer, E. W., Kanumuri, S. R. R., Sharma, A., & Smith, K. E. (2024). Substance Use Disorder Following Consumption of a Novel Synthetic 7-Hydroxymitragynine Product. Journal of Addiction Medicine, 10-1097.
2. Anand, A., & Hosanagar, A. (2022). The addictive potential and challenges with use of the “herbal supplement” kratom: a case report and literature review. Pain Medicine, 23(1), 4-9.
3. Hill, K., Boyer, E. W., Grundmann, O., & Smith, K. E. (2025). De facto opioids: Characterization of novel 7-hydroxymitragynine and mitragynine pseudoindoxyl product marketing. Drug and Alcohol Dependence, 272, 112701.
4. Prevete, E., Hupli, A., Marrinan, S., Singh, D., D’Udine, B., Bersani, G., ... & Corazza, O. (2021). Exploring the use of Kratom (Mitragyna speciosa) via the YouTube data tool: A novel netnographic analysis. Emerging trends in drugs, addictions, and health, 1, 100007.
5. Piyapanyamongkhon, P. (2025). Seizures associated with kratom (Mitragyna speciosa) use: A systematic review of published case reports. Public Health Toxicology, 5(3), 1-9.
6. Alsbrook, S., Pro, G., & Koturbash, I. (2025). From kratom to 7-hydroxymitragynine: evolution of a natural remedy into a public-health threat. Pharmaceutical Biology, 63(1), 896-911.
“Natural” doesn’t always mean safe. Many modern products are highly concentrated extracts with unpredictable strength. This seems particularly true with kratom and 7-OH, because there is so much money involved and so little regulation.
Not exactly. It’s a much stronger version of one of kratom’s active ingredients, and it can cause withdrawal and cravings even faster. Don’t be fooled by the hype, these are two different drugs.
Some people try, but withdrawal can be intense. If you’ve been using daily or mixing substances, medical support is the safest route. If you’ve tried at home and it’s not working, it may be time to consider residential treatment.
Because sellers and automated accounts are crowding the internet with positive stories and fake testimonials. Always look for information that cites real research.
Created specifically for those who have loved ones that struggle with addiction.